We offer Application Specific Control Systems for:

Water Purification |  Mixing and Blending  |  Hydrogenation  |  Sterilization  |  Spray Drying
Fermentation  |  Tablet Coating  |  Environmental and Stability Chamber Monitoring
Freeze Drying  |  Time Synchronization

WATER PURIFICATION
Water purity is extremely important to pharmaceutical and biochemical industries. Suspended or dissolved particles, organic compounds, impurities and other contaminants prohibit the usage of tap water in laboratory applications and scientific research. <download application note>

The HYDROGENATION process
Hydrogenation is the chemical addition of hydrogen to a hydrocarbon in the presence of a catalyst, a severe form of hydrogen treating. Hydrogenation may be either destructive or non-destructive. In the former case, hydrocarbon chains are ruptured (cracked) and hydrogen is added where the breaks have occurred. In the latter, hydrogen is added to a molecule that is unsaturated with respect to hydrogen. In either case, the resulting molecules are highly stable. <download application note>

The STERILIZATION process
Through history humans have used fire to purify items. Heat generated through application of high temperatures acts by disrupting membranes and denatruing proteins and nucleic acids. Burning, however is a bit excessive for everyday usage. Transmissible agents (such as spores, bacteria and viruses) can be eleminated through sterilization. This is different from disinfection, where only organisms that can cause disease are removed. <download application note>

The SPRAY DRYING process
The spray drying process is older than might commonly be imagined. Earlier descriptions date from 1860 with the first patented design recorded in 1872. The basic idea of spray drying is the production of highly dispersed powders from a fluid feed by evaporating the solvent. This is achieved by mixing a heated gas with an atomised (sprayed) fluid of high surface-to-mass ration droplets, ideally of equal size, within a vessel (drying chamber), causing the solvent to evaporate uniformly and quickly through direct contact. Spray drying can be used in a wide range of applications where the production of free-flowing powder is required. <download application note>

The FERMENTATION process
Fermentation is a batch process widely used within the Pharmaceutical and Food industries. It requires the cultivation in submerged culture of an identified micro-organism (mainly bacterial) as a monoculture under defined environmental conditions. The incubation regime imposed is designed to maximize the productivity of the organism of interest by providing optimal conditions for population growth (biomass). The product of interest might be a bioactive metabolite or recombinant protein. <download application note>

TABLET COATING
Many solid pharmaceutical dosage mediums are produced with coatings, either on the external surface of tablets, or on materials dispensed within gelatine capsules. Coating serves a number of purposes; Protects the tablet (or the capsule contents) from stomach acids; Protects the stomach lining from aggressive drugs such as entericcoated aspirin; Provides a delayed release of the medication; Helps maintain the shape of the tablet. <download application note>

PHARMACEUTICAL ENVIRONMENTAL and STABILITY CHAMBER MONITORING
Monitoring of storage and production environments has become an important issue within the Pharmaceutical Industry. The FDA and other regulatory bodies require not only accurate measurement and storage of room parameters but if the storage medium is electronic then the methods used must comply with 21 CFR Part 11. <download application note>

FREEZE DRYING
Freeze drying is a slow batch process used in pharmaceutical & biochemical industries to extract dry product from an aqueous solution. The product is usually in phials placed on shelves in a vacuum chamber, which is first frozen and then evacuated. The shelves are then warmed up very slowly, boiling off the liquid, whilst the chamber is continuously evacuated through a cold condenser. Once above zero degrees the chamber isolation valve is closed and a ‘Pressure Rise Test’ is performed to ensure the product is dry. <download application note>

TIME SYNCHRONIZATION
If the correct time and date are an important part of your data acquisition, the 5000 Series of recorders are designed to make life easy. In today’s age of Electronic Records, accurate time stamps are an important part of the information recorded. <download application note>

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